IceGiant ProSiphon Elite
Specifications

Yes! The ProSiphon Elite is compatible with AMD's new Ryzen 5000 series processors (AM4 socket)! 

Fan Specifications

But will it cover my Threadripper chip (TR4/sTR4x sockets)???

Yes.

Operational Orientation

Unlike a typical thermosiphon design, the patented ProSiphon technology is engineered to operate in either the horizontal or vertical orientation (with respect to the motherboard).